Binding Studies of a New Water-Soluble Iron(III) Schiff Base Complex to DNA Using Multispectroscopic Methods

نویسندگان

  • Nahid Shahabadi
  • Zeinab Ghasemian
  • Saba Hadidi
چکیده

A novel iron(III) complex [Fe(SF)](ClO(4))(3).2H(2)O; in which SF = N,N(0)-bis{5-[(triphenylphosphonium chloride)-methyl] salicylidene}-o-phenylenediamine) has been synthesized and characterized using different physicochemical methods. The binding of this complex with calf thymus (CT) DNA was investigated by circular dichroism, absorption studies, emission spectroscopy, voltammetric studies, and viscosity measurements. The results showed that this complex can bind to DNA via external and groove binding modes.

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عنوان ژورنال:

دوره 2012  شماره 

صفحات  -

تاریخ انتشار 2012